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Cagrilintide is a synthetic long-acting analog of amylin, a 37-amino acid hormone naturally co-secreted with insulin from pancreatic beta cells. It features specific amino acid substitutions and a fatty acid acylation that slows clearance from solution. The compound has the molecular formula C194H312N54O59S2, a molecular weight of approximately 4,409 g/mol, and CAS number 1415456-99-3. It is supplied as a white lyophilized powder, soluble in water. The fatty acid sidechain enables albumin binding and extends persistence compared to native amylin. This product is strictly for research purposes only.
ℹ️ Note: 1 kit includes 10 vials
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Cagrilintide is a synthetic analog of amylin, a 37-amino acid peptide hormone that is naturally co-secreted with insulin from pancreatic beta cells. Cagrilintide was designed as a long-acting version of the native amylin molecule, with specific amino acid substitutions and an acylation — the attachment of a fatty acid chain — that slows its clearance from solution.
The compound has the molecular formula C194H312N54O59S2, a molecular weight of approximately 4,409 g/mol, and a CAS number of 1415456-99-3. It is classified as an acylated amylin receptor agonist. Cagrilintide is supplied as a white lyophilized powder that is soluble in water. The key structural modification is the fatty acid sidechain, which enables albumin binding and extends the molecule’s half-life substantially compared to native amylin, which breaks down within minutes in solution.
This product is strictly for research purposes only. Not approved for human or animal use.
PubChem Reference: View compound profile on NIH PubChem
Formula: C194H312N54O59S2
Weight: 4,409 g/mol
CAS: 1415456-99-3
Structure: Modified amylin analog
Form: White lyophilized powder
Solubility: Soluble in water
Half-life: Extended compared to native amylin
Storage: Keep refrigerated 36‑46 °F (2‑8 °C)
| Weight | 5mg, 10mg |
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Prof. Gregory S. Whitman –
A superior synthetic amylin analog. The specific amino acid substitutions reduce aggregation compared to native peptide. My postdocs noted reproducible results in replicate experiments highly
Dr. Fatima Z. El-Sayed –
Very effective in our in vivo pharmacokinetic trials. The long duration of action allowed for once-daily dosing in animal models. Shipping was prompt and lyophilized powder arrived intact
Prof. David K. Murakami –
Perfectly matched the published molecular weight of 4.3 kDa via MALDI-TOF. Solubility in alkaline buffer was excellent. Reliable supplier for long-acting peptide studies
Dr. Rebecca T. Lawson –
Exceptional purity and consistency across multiple batches. The fatty acid acylation delivers the expected extended half-life in our rodent models. Gold standard for amylin analog research in my lab
Dr. Anita K. Patel –
Good value for the price range ($110–$168). Activity in receptor binding assays matched literature values within 5%. Would appreciate slightly faster dry ice shipment, but overall excellent product
Prof. Lars E. Johansson –
Flawless performance in both cell-based and biochemical assays. The C194H312N62O50S7 composition was verified by our lab’s elemental analysis. Already placed a repeat order for our metabolic research cohort