Description
TB-500 is the synthetic form of Thymosin Beta-4, a 43-amino-acid peptide with the molecular formula C212H350N56O78S and a molecular weight of 4,963.4 g/mol. The naturally occurring version of this peptide was first isolated from calf thymus tissue in the 1960s during research into thymus gland extracts. TB-500 corresponds to the active region of the full Thymosin Beta-4 sequence.
Structurally, Thymosin Beta-4 is an unstructured, highly flexible peptide in solution, meaning it does not fold into a fixed three-dimensional shape the way many larger proteins do. It contains a central actin-binding domain — a stretch of amino acids structurally complementary to actin, one of the most common structural proteins in biology. The compound is identified by CAS number 77591-33-4 and appears as a white to off-white lyophilized powder that is soluble in water. It should be stored frozen for long-term stability.
This product is strictly for research purposes only.
PubChem Reference: View compound profile on NIH PubChem
This product is strictly for research purposes only. Not approved for human or animal use.
Key Characteristics
MOLECULAR PROFILE
Formula: C212H350N56O78S
Weight: 4963.4 g/mol
CAS: 77591-33-4
Structure: 43 amino acid peptide
PHYSICAL PROPERTIES
Form: Lyophilized powder
Solubility: Water-soluble
Appearance: White to off-white powder
Storage: Store in freezer for long-term stability
Marcus Chen –
Excellent quality TB-500. The CAS number (77591-33-4) matched, and the vacuum seal was intact. Shipping to the US took only 4 days. PeptidesVital is now my primary vendor for research peptides
Lauren Foster –
Very impressed with the quality of TB-500. The peptide is clean and dissolves perfectly. Customer service responded to my shipping question within hours. Five stars all the way
Dr. Amir Hassan –
International shipping was seamless. TB-500 arrived well-packaged with clear labeling. Purity appears excellent based on our initial analysis. Highly recommend PeptidesVital for serious researchers
Dr. Victor Nguyen –
Ordered TB-500 for a long-term project. All vials arrived with intact vacuum seals and consistent cake formation. No degradation products detected. PeptidesVital delivers exactly what they promise
Dr. Rachel Simmons –
TB-500 arrived quickly and in perfect condition. The lyophilized powder reconstituted smoothly with no particulates. Our research on actin regulation has been highly reproducible with this batch. Will definitely order again
Dr. Oliver Schmidt –
Reliable vendor with genuine TB-500. The CAS number checked out, and the peptide performed flawlessly across multiple assays. International delivery to Germany was faster than expected. Will reorder
Jessica Taylor –
Third time purchasing TB-500 from this site. Every vial has been consistent — no clumping, easy reconstitution, and our lab results have been rock solid. Free shipping over $200 is a nice bonus
Samantha Brooks –
Fast shipping, secure packaging, and great product. TB-500 reconstituted crystal clear and worked perfectly in our in vivo models. Will be ordering the bulk option next time. Highly satisfied