Description
SS-31 is a synthetic tetrapeptide — a chain of four amino acids with the sequence D-Arg-Dmt-Lys-Phe-NH2. “Dmt” stands for 2′,6′-dimethyltyrosine, a modified version of the natural amino acid tyrosine. The molecular formula is C32H49N9O5, and it has a molecular weight of approximately 639.8 g/mol. Its CAS registry number is 736992-21-5. The peptide carries a net positive charge at physiological pH due to the arginine and lysine residues.
SS-31 belongs to a class of mitochondria-targeted tetrapeptides designed with mitochondrial membrane-compatible structural features. The peptide’s small size and alternating aromatic-cationic motif (positive charge, aromatic ring, positive charge, aromatic ring) give it membrane-permeable characteristics. It has a structural affinity for cardiolipin, a phospholipid found almost exclusively in the inner mitochondrial membrane. SS-31 is supplied as a white to off-white lyophilized powder that is soluble in water.
This product is strictly for research purposes only. Not approved for human or animal use.
PubChem Reference: View compound profile on NIH PubChem
Key Characteristics
MOLECULAR PROFILE
Formula: C₃₂H₄₉N₉O₅
Weight: 639.8 g/mol
CAS: 736992-21-5
Sequence: D-Arg-Dmt-Lys-Phe-NH₂
PHYSICAL PROPERTIES
Form: White to off-white lyophilized powder
Solubility: Water-soluble
Storage: Keep refrigerated 36‑46 °F (2‑8 °C)
Stability: Stable when properly stored





Jason Park –
First time ordering SS-31 from this vendor. CAS number (736992-21-5) matched perfectly. Vacuum seal was intact, and shipping was faster than expected. Will definitely be a repeat customer
Dr. Michelle Reynolds –
Excellent quality SS-31. I’ve tested peptides from several suppliers, and PeptidesVital ranks among the best. The product is clean, soluble, and consistent. Free shipping over $200 is a great perk
Dr. Anita Desai –
Very happy with my purchase. SS-31 reconstituted crystal clear and showed no signs of peptide aggregation. The price is fair for the quality offered. Will recommend to colleagues
Dr. Elena Vasquez –
SS-31 arrived promptly and in excellent condition. The lyophilized powder reconstituted beautifully with no residue. Our mitochondrial research depends on high-purity peptides, and this batch delivered. Highly recommend PeptidesVital
Dr. Sophia Chen –
International shipping was smooth and well-tracked. SS-31 arrived in perfect shape with clear labeling. The peptide performed exactly as expected in our assays. PeptidesVital is now my go-to supplier
Christopher Lane –
PeptidesVital consistently delivers top-notch products. SS-31 arrived well-packaged with documentation. Our lab has seen reproducible results across multiple trials. Definitely ordering in bulk next time
Brian Foster –
Reliable vendor with great customer support. Highly satisfied
Kevin Anderson –
Ordered SS-31 for a new research protocol. Very impressed with the purity and packaging. Customer service answered my questions about storage quickly. Five stars will order again