GHRP-2 (pralmorelin) is a synthetic hexapeptide — a chain of six amino acids with the sequence D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2. It has a molecular formula of C45H55N9O6, a molecular weight of 817.99 g/mol, and a CAS number of 158861-67-7. The peptide incorporates two unnatural D-amino acids and the non-standard residue D-2-naphthylalanine, giving it a structure distinct from naturally occurring peptides. GHRP-2 was developed…
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GHRP-6 is a synthetic hexapeptide with the amino acid sequence His-D-Trp-Ala-Trp-D-Phe-Lys-NH2. Its molecular formula is C46H56N12O6, its molecular weight is 873.01 g/mol, and its CAS number is 87616-84-0. The peptide contains two D-amino acids (D-tryptophan and D-phenylalanine), which are mirror-image forms of their natural counterparts that increase the molecule’s resistance to enzymatic degradation. GHRP-6 was first synthesized in the 1980s,…
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GLP1-S is a synthetic analog of glucagon-like peptide-1 (GLP-1), a hormone naturally produced in the intestines. It has a molecular weight of 4,113.64 g/mol and the formula C187H291N45O59 (CAS 910463-68-2). First described in 2007, it is classified as a GLP-1 receptor agonist. Key structural modifications include the substitution of alanine with alpha-aminoisobutyric acid (Aib) at position 8 and the attachment of…
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GLP2-T is a research-designated synthetic 39-amino acid peptide classified as a dual GIP/GLP-1 receptor ligand. First described in patent filings around 2016, the molecule is built on a GIP backbone with a C20 fatty diacid modification — a lipidation strategy common in modern peptide analog design. It has the molecular formula C225H348N48O68, a weight of approximately 4,810.52 g/mol, and CAS number…
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Ipamorelin is a synthetic pentapeptide — a chain of five amino acids — with the sequence Aib-His-D-2-Nal-D-Phe-Lys. It has a molecular weight of 711.86 g/mol and the formula C38H49N9O5 (CAS 170851-70-4). First described in the mid-1990s, it is classified as a growth hormone secretagogue (GHS), a category of compounds designed to interact with the ghrelin/GHS receptor. Its structure includes two non-standard…
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Kisspeptin-10 is a decapeptide — a chain of ten amino acids — with the sequence Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂. It is the shortest bioactive fragment of the kisspeptin-54 protein, which is encoded by the KISS1 gene, first identified in 1996 at Pennsylvania State University. The peptide has the molecular formula C₆₃H₈₃N₁₇O₁₄, a molecular weight of 1302.45 g/mol, and CAS number 374675-21-5. The C-terminal…
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KPV is a synthetic tripeptide made up of three amino acids: lysine (K), proline (P), and valine (V). It has the molecular formula C16H29N3O4, a molecular weight of 327.42 g/mol, and CAS number 67727-97-3. KPV corresponds to positions 11-13 of alpha-melanocyte-stimulating hormone (alpha-MSH), a 13-amino-acid neuropeptide produced in the pituitary gland. It represents the C-terminal fragment — the last three…
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Melanotan 1 (afamelanotide) is a synthetic linear peptide composed of 13 amino acids, designed as an analog of the naturally occurring alpha-melanocyte-stimulating hormone (alpha-MSH). It has the molecular formula C78H111N21O19, a molecular weight of 1646.85 g/mol, and a CAS number of 75921-69-6. First synthesized in the 1980s, Melanotan 1 was engineered by modifying the native alpha-MSH sequence to increase chemical…
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Melanotan 2 (MT-2) is a synthetic cyclic heptapeptide — a ring-shaped chain of seven amino acids — and an analog of alpha-melanocyte-stimulating hormone (alpha-MSH). It has the molecular formula C50H69N15O9, a molecular weight of 1024.20 g/mol, and a CAS number of 121062-08-6. Its defining structural feature is a lactam bridge, an internal bond that closes the amino acid chain into…
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MOTS-c is a 16-amino-acid peptide with the molecular formula C101H152N28O22S2 and a molecular weight of 2,174.6 g/mol (CAS 1627580-64-6). First described in 2015, MOTS-c is unusual because it is encoded by mitochondrial DNA rather than nuclear DNA. It belongs to a class called mitochondrial-derived peptides (MDPs) — short peptides encoded within the mitochondrial genome. Its sequence (MRWQEMGYIFYPRKLR) is found within the…
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