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GLP1-S is a synthetic analog of glucagon-like peptide-1 (GLP-1), a hormone naturally produced in the intestines. It has a molecular weight of 4,113.64 g/mol and the formula C187H291N45O59 (CAS 910463-68-2). First described in 2007, it is classified as a GLP-1 receptor agonist. Key structural modifications include the substitution of alanine with alpha-aminoisobutyric acid (Aib) at position 8 and the attachment of a C-18 fatty diacid side chain at position 26, a modification common in long-acting peptide analogs. These structural differences distinguish GLP1-S from the native GLP-1 peptide. It appears as a white lyophilized powder that is soluble in water. This product is strictly for research purposes only.
ℹ️ Note: 1 kit includes 10 vials
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GLP1-S is a synthetic analog of glucagon-like peptide-1 (GLP-1), a naturally occurring hormone produced in the intestines. Its molecular formula is C187H291N45O59, with a molecular weight of 4,113.64 g/mol (CAS 910463-68-2). First described in the scientific literature in 2007, it is classified as a GLP-1 receptor agonist — a synthetic analog structurally derived from the native GLP-1 peptide.
What distinguishes GLP1-S from the native hormone is a series of structural modifications. A key change is the substitution of alanine at position 8 with alpha-aminoisobutyric acid (Aib), a substitution that distinguishes it from the native GLP-1 sequence. Additionally, a C-18 fatty diacid chain is attached via a linker at position 26, a modification shared with other long-acting peptide analogs. These chemical changes distinguish GLP1-S structurally from the native 30-amino-acid GLP-1 peptide, which breaks down within minutes. In its research-grade form, GLP1-S appears as a white lyophilized powder that is soluble in water.
This product is strictly for research purposes only. Not approved for human or animal use.
PubChem Reference: View compound profile on NIH PubChem
Formula: C₁₈₇H₂₉₁N₄₅O₅₉
Weight: 4113.641 g/mol
CAS: 910463-68-2
Structure: Modified GLP-1 analog
Form: White lyophilized powder
Solubility: Water-soluble
Half-life: Extended duration
Storage: Keep refrigerated 36‑46 °F (2‑8 °C)
| Weight | 5mg |
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Dr. Sophia L. Bennett –
Solid GLP1-S works exactly as expected in our insulin secretion assays. The lyophilized powder arrived intact with prompt shipping to Canada. Minor note: a longer expiration date would be appreciated, but quality is excellent
Prof. James T. Harrington –
Very reliable peptide for incretin research. Reconstitutes easily and remains stable in solution for up to 48 hours. Would give 5 stars if the vial included a desiccant packet, but the product itself is top-notch
Dr. Fatima Z. Al-Mansoori –
performance across multiple batches. GLP1-S from Peptides Vital outperformed samples from two other vendors in our cAMP activation assays. Highly recommend for any GLP-1 receptor studies.
Dr. Elena R. Hofmann –
Excellent quality GLP1-S. Our GLP-1 receptor activation assays showed potent and reproducible results. CAS 910463-68-2 confirmed via LC-MS. The 99% purity claim is accurate no visible impurities
Prof. Lukas P. Novak –
Consistent 99% purity as advertised. Our HPLC analysis showed a single sharp peak with no degradation byproducts. CAS 910463-68-2 verified. Will definitely reorder for our ongoing metabolic research