Description
Delta sleep-inducing peptide (DSIP) is a naturally occurring nonapeptide — a chain of nine amino acids — with the sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu. Its molecular formula is C35H48N10O15, with a molecular weight of 848.81 g/mol (CAS 62568-57-4). DSIP was first isolated in 1977 from the cerebral venous blood of rabbits during induced sleep by a Swiss research group.
The peptide is classified as amphiphilic, meaning it has both water-attracting and water-repelling regions, a property related to its mixed hydrophilic and hydrophobic amino acid residues. The tryptophan residue at the N-terminus gives it a characteristic UV absorbance profile used for laboratory identification. DSIP is notable for its low molecular weight and amphiphilic structure — the selective membrane separating circulating blood from brain tissue. In its research-grade form, it appears as a white lyophilized powder that dissolves in water.
This product is strictly for research purposes only. Not approved for human or animal use.
PubChem Reference: View compound profile on NIH PubChem
Key Characteristics
MOLECULAR PROFILE
Formula: C35H48N10O15
Weight: 848.81 g/mol
CAS: 62568-57-4
Structure: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
PHYSICAL PROPERTIES
Form: White lyophilized powder
Solubility: Water-soluble
BBB Penetration: Crosses blood-brain barrier
Storage: Keep refrigerated 36‑46 °F (2‑8 °C)





Dr. Helena M. Strauss –
Delta sleep-inducing peptide performed exactly as expected in our chronobiology studies. The 99% purity was confirmed via reverse-phase HPLC. Reliable source for this delicate 9-amino acid peptide.”
2. Prof. Andre L. Bouchard
Dr. Priya K. Mehta –
Consistent bioactivity across three separate batches. CAS 62568-57-4 verified in our lab. Ideal for in vitro studies on delta wave regulation. One of the cleaner neuropeptides we’ve sourced this quarter
Prof. Henrik S. Vestergaard –
Perfect for our receptor binding assays. The 99% purity claim held up under mass spectrometry. No unexpected peaks. DSIP from this supplier has become a staple in our neuropeptide library
Dr. Camila R. Flores –
Good stability when stored at -20°C. DSIP showed expected activity in our simulated CSF models. Purity meets research standards. Only minor note the vial could be slightly larger for easier handling, but product quality is solid
Prof. Andre L. Bouchard –
Clean product with no detectable degradation byproducts. DSIP is notoriously tricky to handle, but this lyophilized formulation reconstituted smoothly. Would appreciate slightly faster international shipping, but the peptide quality is excellent.