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GHK-Cu is a copper-binding tripeptide — a chain of three amino acids (glycine, histidine, and lysine) bound to a copper(II) ion. Its molecular formula is C14H21CuN6O4, with a molecular weight of 404.9 g/mol and CAS number 89030-95-5. The peptide was first identified in 1973 by Loren Pickart during research on human plasma, where he observed that a small copper-peptide complex was present in younger blood samples at higher concentrations than in older ones.
The copper ion is coordinated to the peptide through the nitrogen atoms of the glycine and histidine residues, giving the compound its distinctive blue color in crystalline form. This type of metal-peptide complex is relatively unusual among research peptides. GHK-Cu is naturally found in trace amounts in human plasma, saliva, and urine. It is classified as a metallopeptide — a peptide that incorporates a metal ion as part of its structure. The compound is supplied as a blue crystalline powder, highly soluble in water, and should be stored refrigerated at 36-46 degrees F (2-8 degrees C) and protected from light.
This product is strictly for research purposes only.
PubChem Reference: View compound profile on NIH PubChem
This product is strictly for research purposes only. It is not approved for human or animal use and should only be handled by qualified researchers in appropriate laboratory settings.
Formula: C14H21CuN6O4
Weight: 404.9 g/mol
CAS: 89030-95-5
Structure: Gly-His-Lys (with bound copper)
Form: Blue crystalline powder (the blue color comes from the copper)
Solubility: Highly water-soluble
Natural Occurrence: Found in human plasma, saliva, and urine
Storage: Keep refrigerated 36–46 °F (2–8 °C), protect from light
| Weight | 50mg, 100mg |
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Dr. Sofia L. Monteiro –
Truly remarkable batch-to-batch consistency. GHK-Cu from Peptides Vital outperformed two other major vendors in our collagen synthesis ELISA. Copper content was spot-on. A five-star product across every metric
Dr. Jasmine K. Thorne –
Best GHK-Cu we’ve used in five years. The 99% purity claim is honest our HPLC showed 99.3%. Minimal free copper contamination, which is a common issue with cheaper sources. This will be our exclusive supplier going forward
Prof. Anders E. Nordström –
Flawless every time. Matrix metalloproteinase inhibition assays gave textbook results. The price point ($33–$64) is excellent for this level of quality. Lyophilized powder reconstitutes immediately. Can’t recommend enough
Prof. Miguel R. Herrera –
Remarkable stability compared to other suppliers we’ve tested. GHK-Cu retained full bioactivity for weeks when stored properly. CAS 89030-95-5 verified. A true workhorse for our wound healing and anti-aging research models