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Epithalon (also spelled Epitalon or Epithalone) is a synthetic tetrapeptide — a chain of four amino acids — with the sequence Ala-Glu-Asp-Gly. It has a molecular weight of 390.34 g/mol and the formula C14H22N4O9 (CAS 307297-39-8). It was first synthesized in the 1990s, modeled on the amino acid composition of epithalamin, a peptide extract from the bovine pineal gland. Epithalon is among the smallest peptides studied in bioregulation research. Its sequence contains two acidic residues — glutamic acid and aspartic acid — giving the molecule a net negative charge at physiological pH. It appears as a white lyophilized powder, dissolves readily in water, and requires refrigerated storage. This product is strictly for research purposes only.
ℹ️ Note: 1 kit includes 10 vials
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Epithalon (also spelled Epitalon or Epithalone) is a synthetic tetrapeptide — a chain of four amino acids — with the sequence Ala-Glu-Asp-Gly. Its molecular formula is C14H22N4O9, with a molecular weight of 390.34 g/mol (CAS 307297-39-8). It was first synthesized in the 1990s, based on the amino acid composition of epithalamin, a peptide extract derived from the bovine pineal gland.
As a tetrapeptide, Epithalon is one of the smallest biologically studied peptides. Its four-residue sequence — alanine, glutamic acid, aspartic acid, and glycine — gives it two acidic side chains, making the molecule negatively charged at physiological pH. It dissolves readily in water and appears as a white lyophilized powder in its research-grade form.
This product is strictly for research purposes only. Not approved for human or animal use.
PubChem Reference: View compound profile on NIH PubChem
Formula: C14H22N4O9
Weight: 390.34 g/mol
CAS: 307297-39-8
Structure: Ala-Glu-Asp-Gly
Form: White lyophilized powder
Solubility: Readily dissolves in water
Origin: Synthetic version of epithalamin
Storage: Keep refrigerated 36‑46 °F (2‑8 °C)
| Weight | 10mg, 50mg |
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Prof. Wei-Cheng Lin –
Perfect match for the published amino acid sequence. Our mass spec confirmed identity with no contaminants. Reliable source for Epithalon will definitely reorder for our ongoing epigenetic studies.
Dr. Lena M. Hofstadter –
Consistent results across three separate orders. Epithalon is a delicate tetrapeptide, yet this supplier delivered excellent purity each time. Ideal for research on pineal gland peptides and aging models
Prof. George K. Alexandrou –
Clean peptide with no unexpected degradation peaks. CAS 307297-39-8 verified in our lab. The lyophilized powder reconstituted easily in saline. Would give 5 stars if the vial had a resealable cap, but the quality itself is top-notch
Dr. Fatima A. Rahman –
Good stability in solution over 24 hours. The 99% purity claim held up under our analysis. Research-grade quality at a fair price. Minor delay in shipping to the UAE, but product was well-packaged and intact
Dr. Svetlana O. Morozova –
Epithalon performed excellently in our in vitro telomerase expression studies. The 99% purity was confirmed via HPLC. Stable tetrapeptide with reliable bioactivity across multiple experiments