Oxytocin

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Oxytocin is a cyclic nonapeptide with the sequence Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2, forming a ring through a disulfide bond between its two cysteine residues. First synthesized in 1953 by Vincent du Vigneaud, whose work later earned him the Nobel Prize in Chemistry, oxytocin holds the distinction of being the first peptide hormone ever produced synthetically in a laboratory, a landmark moment in the history of peptide chemistry. It has the molecular formula C43H66N12O12S2, molecular weight 1,007.19 g/mol, CAS 50-56-6. Naturally produced in the hypothalamus, it is classified as both a neuropeptide and a peptide hormone. Supplied as a white to off-white lyophilized powder, highly soluble in water. This product is strictly for research purposes only.

ℹ️ Note: 1 kit includes 10 vials

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Description

 Oxytocin is a cyclic nonapeptide, a chain of nine amino acids arranged in a ring shape held together by a disulfide bond between two cysteine residues. Sequence Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2, molecular weight 1,007.19 g/mol, formula C43H66N12O12S2, CAS 50-56-6.

Oxytocin’s synthesis in 1953 by Vincent du Vigneaud was a watershed moment in peptide chemistry, it was the first polypeptide hormone ever synthesized in a laboratory, work that earned du Vigneaud the 1955 Nobel Prize in Chemistry. This historical significance is part of why oxytocin remains such a heavily referenced compound in peptide research broadly, beyond its own specific biological effects. The compound is naturally produced in the hypothalamus and released by the posterior pituitary, and is classified as both a neuropeptide (acting within the brain) and a peptide hormone (acting systemically), a dual role that has made it a subject of research spanning social behavior, reproductive physiology, and stress regulation.

In its research-grade form, oxytocin appears as a white to off-white lyophilized powder that is highly soluble in water. This product is strictly for research purposes only.

PubChem Reference: View compound profile on NIH PubChem

This product is strictly for research purposes only. Not approved for human or animal use.

Key Characteristics

MOLECULAR PROFILE

Formula: C43H66N12O12S2

Weight: 1007.19 g/mol

CAS: 50-56-6

Structure: Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly

PHYSICAL PROPERTIES

Form: White to off-white lyophilized powder

Solubility: Highly soluble in water

Alternative Names: α-Hypophamine, Ocytocin, Syntocinon

Storage: Cool, dry place away from light

Oxytocin in Published Research

Oxytocin research spans an unusually broad range of fields given its dual neuropeptide/hormone classification. Published research has investigated its role in social bonding and trust behavior, uterine contraction and lactation physiology (its original discovered function), and more recently its interaction with stress and anxiety pathways. Because it was the first peptide hormone ever synthesized, it also holds a foundational place in the history of peptide chemistry techniques more broadly.

Frequently Asked Questions :

What is Oxytocin studied for in research?

Social bonding behavior, reproductive physiology (uterine contraction, lactation), and stress/anxiety regulation, given its dual role as both a neuropeptide and hormone.

Why is Oxytocin historically significant?

It was the first peptide hormone ever chemically synthesized (1953), work that earned Vincent du Vigneaud the Nobel Prize in Chemistry.

What are its alternative names?

Also known as α-Hypophamine, Ocytocin, and Syntocinon in older or pharmaceutical literature.

How should it be reconstituted and stored?

Bacteriostatic water, store in a cool, dry place away from light.

Where can I buy it?

2mg kit, HPLC/MS verified.

Additional information

Weight

2mg

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